On the other hand, K2 is often considerably much more potent and unsafe than natural cannabis, with a wide array of unpredictable Unwanted side effects.
Synthetic cannabinoids were produced for cannabinoid analysis concentrating on tetrahydrocannabinol (THC), cannabinoid receptors, plus the endocannabinoids that activate them in the human body. Synthetic cannabinoids ended up desired partly due to lawful limits on natural cannabinoids, which make them difficult to obtain for research.
Numerous are practical mainly because they bind selectively to both the CB1 or CB2 receptors, whereas THC has an analogous affinity for equally. Tritium-labelled cannabinoids such as CP-55,940 had been instrumental in exploring the cannabinoid receptors in the early nineteen nineties.[fifty three]
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